Conte Lab
Department of Surgery Websites

Lab Director

Professor & Chief,
Division of Vascular & Endovascular Surgery

Co-Director, UCSF Heart and Vascular Center

Support the Lab

A gift to the Conte Lab helps support research to treat serious conditions such as PAD, aneurysms, and carotid artery disease.

Mechanisms of vascular injury and remodeling

The Conte Lab conducts basic laboratory investigations that are focused on understanding and improving the healing response of blood vessels following angioplasty and bypass surgery, with the goal of improving the long-term results of these common operations. Specifically, the laboratory investigates the vascular biology of restenosis and the vessel wall response to injury. We are interested in the molecular pathways which govern the survival and growth of endothelial and smooth muscle cells at site of blood vessel injury. We have also had a long-standing interest in the local delivery of genes, small molecules and drugs to blood vessels. His research is funded by the National Institutes of Health and other extramural sources.

Recent Publications

Ho KJ, Spite M, Owens CD, Lancero H, Kroemer AH, Pande R, Creager MA, Serhan CN, Conte MS
Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis.
The American journal of pathology, Oct-01-2010; 1774: 2116-23.  Epub 2010 Aug 13.
Conte MS
Challenges of distal bypass surgery in patients with diabetes: patient selection, techniques, and outcomes.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, Sep-01-2010; 523 Suppl: 96S-103S.
Rybicki FJ, Mitsouras D, Owens CD, Whitmore A, Gerhard-Herman M, Wake N, Cai T, Zhou Q, Conte MS, Creager MA, Mulkern RV
Multi-contrast high spatial resolution black blood inner volume three-dimensional fast spin echo MR imaging in peripheral vein bypass grafts.
The international journal of cardiovascular imaging, Aug-01-2010; 266: 683-91.  Epub 2010 Mar 24.
Owens CD, Kim JM, Hevelone ND, Hamdan A, Raffetto JD, Creager MA, Conte MS
Novel adipokines, high molecular weight adiponectin and resistin, are associated with outcomes following lower extremity revascularization with autogenous vein.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, May-01-2010; 515: 1152-9.  Epub 2010 Mar 11.
Conte MS
Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) and the (hoped for) dawn of evidence-based treatment for advanced limb ischemia.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, May-01-2010; 515 Suppl: 69S-75S.
Conte MS, Geraghty PJ, Bradbury AW, Hevelone ND, Lipsitz SR, Moneta GL, Nehler MR, Powell RJ, Sidawy AN
Suggested objective performance goals and clinical trial design for evaluating catheter-based treatment of critical limb ischemia.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, Dec-01-2009; 506: 1462-73.e1-3.  Epub 2009 Nov 7.
Conte MS, Nugent HM, Gaccione P, Guleria I, Roy-Chaudhury P, Lawson JH
Multicenter phase I/II trial of the safety of allogeneic endothelial cell implants after the creation of arteriovenous access for hemodialysis use: the V-HEALTH study.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, Dec-01-2009; 506: 1359-68.e1.
Conte MS
Technical factors in lower-extremity vein bypass surgery: how can we improve outcomes?.
Seminars in vascular surgery, Dec-01-2009; 224: 227-33.
Owens CD, Wake N, Conte MS, Gerhard-Herman M, Beckman JA
In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, Nov-01-2009; 505: 1063-70.  Epub 2009 Aug 12.
Schanzer A, Goodney PP, Li Y, Eslami M, Cronenwett J, Messina L, Conte MS, Conte MS
Validation of the PIII CLI risk score for the prediction of amputation-free survival in patients undergoing infrainguinal autogenous vein bypass for critical limb ischemia.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter, Oct-01-2009; 504: 769-75; discussion 775.  Epub 2009 Jul 22.
Mitsouras D, Owens CD, Conte MS, Ersoy H, Creager MA, Rybicki FJ, Mulkern RV
In vivo differentiation of two vessel wall layers in lower extremity peripheral vein bypass grafts: application of high-resolution inner-volume black blood 3D FSE.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, Sep-01-2009; 623: 607-15.
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